In a city where the lights never go out, New York’s Upper East Side shines brightest. Oozing glitz and glamour around every corner, the famed city district has derived much of its notoriety from the plethora of books and TV shows that have eulogised this prime real estate of Manhattan over the past century.

Plumped pretty in the middle of the designer boutiques and celebrity hangouts sits the Art Deco masterpiece of The Mark Hotel. A beautiful 1920s landmark building, the property is home to 152 rooms and suites that espouse a sense of tranquillity, thanks to a canvas of creams, white and browns and large-scale, contemporary photography walls. The pièce de résistance of the collection is the hotel's mega-accommodation, The Mark Penthouse.

Sprawling over 1,115 square metres, this bi-level sanctuary has been imagined by renowned designer Jacques Grange and enjoys the title of North America’s largest hotel penthouse – no small feat in a region where accommodation size matters. Boasting five bedrooms, six bathrooms, four fireplaces, two powder rooms and two wet bars, The Mark Penthouse lends itself as the perfect bolthole for families and groups in search of some down time away from the bustling sidewalks of Manhattan. The living room can be transformed into a full-size ballroom for those wishing to host a stylish soirée, with the 232-square-metre terrace serving up panoramic views of Central Park and the island’s skyline.

There’s even a library lounge, grand dining room, conservatory and a state-of-the-art chef’s kitchen featuring state-of-the-art Gaggenau and Miele appliances and sleek cabinetry designed by Piero Lissoni for Boffi, should you wish to show off your culinary skills.

The Mark Penthouse comes with a selection of exclusive benefits to enhance the stay even further. Each day begins with a scrumptious full breakfast and evenings conclude with a cultural excursion: think private after-hours tours of the Metropolitan Museum of Art. There are also complimentary airport transfers and personalised butler service.

When it’s time to stray from this gargantuan area of opulence, the property boasts an array of exceptional gastronomy and wellness offerings. Gastronomes can savour innovative European classics at The Mark Restaurant by Michelin-starred chef Jean-Georges Vongerichten or feast upon twice-baked potato topped with caviar or potato rosti crust caviar pizza with crème fraîche and chives at the legendary Parisian institution Caviar Kaspia.

For wellness, there's a curated selection of services, in-room massages, personal training and an array of facial treatments by renowned aesthetician Dr. Barbara Sturm to elevate the levels of relaxation and pleasure. What’s more, being a per-friendly property, even your four-legged friend can indulge in all the luxury too. The starting rate per night for The Mark Penthouse is from $75,000.

Themarkhotel.com